[Pd(IPr*)(cinnamyl)Cl]: An Efficient Pre‐catalyst for the Preparation of Tetra‐ortho‐substituted Biaryls by Suzuki–Miyaura Cross‐Coupling

The bigger the better: The new well-defined [Pd(IPr*)(cin)Cl] pre-catalyst is described. This complex proves to be highly active in the Suzuki-Miyaura cross-coupling for the synthesis of tetra-ortho-substituted biaryls under mild conditions. IPr* is reported as the largest N-heterocyclic carbene (NHC) to date for [Pd(NHC)(cin)Cl] complexes, explaining the high reactivity observed for this complex in this challenging transformation.