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July 12, 2022Proceedings of the National Academy of SciencesOpen Access

Quantitative NMR analysis of the kinetics of prenucleation oligomerization and aggregation of pathogenic huntingtin exon-1 protein

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Abstract

O sulfoxide species does not nucleate but is still incorporated into fibrils by elongation.

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Ceccon et al. (2022) studied this question.

synapsesocial.com/papers/6a03b3933a92041adea9c745 https://doi.org/10.1073/pnas.2207690119

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