January 1, 2003Seminars in Respiratory and Critical Care Medicine

Bronchiolitis Obliterans Syndrome Complicating Lung or Heart-Lung Transplantation

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Population

Patients with end stage lung diseases undergoing lung or heart-lung transplantation

Design

Review

Authors

JBJohn A. BelperioUniversity of California, Los Angeles KLKathleen D. LakeCincinnati Children's Hospital Medical Center HTHenry D. TazelaarHeart Failure / Cardiomyopathy

Discussion

Member takes

Implication

BOS carries high mortality without proven therapies in lung transplant recipients; leaves open critical gaps in pathogenesis and prevention.

Structured PICO

Population

Patients with end stage lung diseases undergoing lung or heart-lung transplantation

Bronchiolitis obliterans syndrome is a fatal complication of lung and heart-lung transplantation with no proven therapies, necessitating further research into its complex pathogenesis.

Cite This Study

Belperio et al. (2003) studied this question.

synapsesocial.com/papers/6a03bf3dd2c35e4200e969b5 https://doi.org/10.1055/s-2004-815601

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Implication

BOS carries high mortality without proven therapies in lung transplant recipients; leaves open critical gaps in pathogenesis and prevention.