Why the study?
Do maternal cardiac function and uterine artery Doppler at 11-14 weeks predict pre-eclampsia and small for gestational age in nulliparous women?
Population
534 nulliparous women with singleton pregnancies presenting consecutively for routine antenatal care
Design
Cross-sectional
Authors
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Hypothesis-generating for first-trimester prediction in nulliparous women; prospective validation required before clinical adoption.
Do maternal cardiac function and uterine artery Doppler at 11-14 weeks predict pre-eclampsia and small for gestational age in nulliparous women?
Maternal cardiac function and uterine artery Doppler assessments in the first trimester can help predict the subsequent development of pre-eclampsia and small for gestational age in nulliparous women.
Khaw et al. (2008) studied this question.
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