Clinical Outcomes of Implantable Collamer Lenses for the Treatment of Myopia in Eyes with Anterior Chamber Depth (

Purpose: To report the clinical outcomes of ICL implantation for the treatment of myopia in American patients at a single center with central internal anterior chamber depth (ACD) less than the FDA-approved 3.0 mm. Patients and Results: Of the 231 eyes with ACD < 3.0 mm, 0.4% (1/231) required intraocular surgical intervention including ICL explant, exchange, or toric lens repositioning at some point in the postoperative period or were clinically judged to have a vault requiring an exchange compared to 3.7% (26/712) eyes with ACD ≥ 3.0 mm (p = 0.0103). Average postoperative vault for the eyes with ACD < 3.0 mm was 437.22 ± 191.93 microns compared to 560.73 ± 193.65 in eyes with ACD ≥ 3.0 mm (p < 0.001). IOP and visual acuity at 1 month were similar between the groups. Conclusion: Outside the US, the lower limit of ACD is 2.8 mm for myopia correction. This single center study demonstrates that ICL surgery in American eyes with ACDs < 3.0 mm may also be safe and result in excellent outcomes with comparable rates of exchange or enhancement to eyes meeting the FDA guidelines.