This document is the Accepted Manuscript version of a Published Work that appeared in final form in Reviews, copyright © American Chemical Society after peer review and technical editing by the publisher. access the final edited and published work see http://pubs.acs.org/doi/abs/10.1021/cr1002744
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Weaver et al. (2011) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: