The major chemical constituents of Penthorum chinense Pursh and their inhibitory activity against enzymes associated with metabolic dysfunction-associated steatotic liver disease

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Key Points

This research aims to identify the main chemical constituents of Penthorum chinense and assess their effects on enzymes related to metabolic dysfunction-associated liver disease.
Characterization of chemical constituents in Penthorum chinense extracts.
Evaluation of enzyme inhibition activity using specific assays.
Comparative analysis of effectiveness against various enzymes.
Significant inhibitory activity observed against multiple enzymes related to metabolic dysfunction.
Chemical constituents identified include flavonoids and phenolic compounds with strong enzyme inhibition.
Constituents demonstrated varied effectiveness, indicating potential as therapeutic agents for liver disease.

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Inhibitory activity of Penthorum chinense extracts against enzymes linked to metabolic dysfunction in liver disease.

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Wang et al. (2026) studied this question.

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