Case report demonstrates inferior corneal thinning and lipid deposition in a young boy, indicating early diagnosis importance.
Terrien’s marginal degeneration (TMD) is usually a bilateral peripheral corneal thinning disorder, mostly involving the superior cornea, in men aged 20–40 years.[1] A 10-year-old boy with right eye (RE) unaided 6/9, n-6 vision presented with inferior corneal furrowing with lipid deposition [Fig. 1a and c], with on-and-off inflammation, and a normal serology report with inferior steepening in corneal topography [Fig. 1b] and stromal scarring with subepithelial hyperreflective band (central stromal thickness [ST] 612µ, temporal ST 540µ and nasal ST 550µ) in anterior segment optical coherence tomography (ASOCT) [Fig. 1d]. Vest et al.[2] reported the youngest case of TMD in a 6-year-old child with unilateral inferior circumferential corneal thinning. Chan et al.[3] reported the incidence of spontaneous perforation in their series, thus emphasizing the importance of early diagnosis. Rodriguez Marianeli et al.[4] have shown the role of ASOCT in differentiating between the quiescent and inflammatory stages.Figure 1: (a, c) Diffuse slit-lamp picture of right eye showing inferior corneal furrow with lipid deposition. (b) Anterior corneal topography of the right eye showing steepening of the inferior cornea, left eye normal symmetrical bow-tie pattern. (d) ASOCT of the right eye showing stromal thinning with a subepithelial hyperreflective bandAuthors’ contributions Sumana Chatterjee – Concept, Manuscript design, preparation; Jayanta Kuila - Manuscript Review. Declaration of patient consent The authors certify that they have obtained all appropriate patient consent forms. In the form, the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed. Financial support and sponsorship: Nil. Conflicts of interest: There are no conflicts of interest.
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Chatterjee et al. (2026) studied this question.
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