Selenium‐Bearing Conducting Polymer/Graphene Quantum Dot Hybrid for Enzyme Based Electrochemical Biosensor Targeting Tyrosinase Inhibition Via Rosmarinic Acid

May 1, 2026ChemistryOpenOpen Access

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Key Points

This research aims to assess the inhibitory effects of rosmarinic acid on tyrosinase using a novel enzyme-based electrochemical biosensor.
Developed a hybrid of selenium-bearing conducting polymer and graphene quantum dots.
Evaluated tyrosinase activity as the main endpoint for inhibition by rosmarinic acid.
Utilized electrochemical techniques for biosensing measurements.
Demonstrated significant inhibition of tyrosinase activity by rosmarinic acid at varying concentrations.
Achieved a notable decrease in enzyme activity, suggesting effective biosensing capabilities.
Showed enhanced sensitivity and specificity of the electrochemical biosensor for tyrosinase detection.

Evaluates rosmarinic acid effects on tyrosinase inhibition in biosensing applications, indicating potential benefits for enzyme regulation.

-functionalized graphene quantum dots for tyrosinase biosensing to evaluate rosmarinic acid inhibitory effects.

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Alhardan et al. (2026) studied this question.

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