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Identifies a peptide that alleviates oxidative damage in cells, suggesting potential therapeutic use.
-TPTZ) in vitro and promotes the expression of GSH-Px while increasing GSH-Px and SOD enzyme activity to eliminate ROS in LPS-treated EA.hy926 cells. Furthermore, this peptide could reduce the content of ROS and ET-1 in Ang II-induced EA.hy926 cells. The result suggested that WDGL may alleviate EA.hy926 oxidative damage by activating the Keap1-Nrf2 signaling pathway.
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Zhu et al. (2026) studied this question.
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