Why the study?
Does irbesartan improve maximum inspiratory pressure in patients with COPD?
Does irbesartan improve maximum inspiratory pressure in patients with COPD?
In patients with COPD, irbesartan did not improve respiratory muscle strength but significantly decreased haematocrit and total lung capacity.
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Irbesartan should not be used to improve respiratory muscle strength in COPD; challenges hypotheses for RAS inhibition in this population.
Andreas et al. (2006) studied this question.
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