Emerging Polar Phenolic Disinfection Byproducts Are High-Affinity Human Transthyretin Disruptors: An in Vitro and in Silico Study

> 0.700, CCC > 0.850), implying that the model had good goodness-of-fit, robustness, and external prediction performances. All the results indicated that the phenolic-DBPs have the hTTR disrupting effects, and further studies are needed to investigate their other mechanism of endocrine disruption.