The association between body mass index and mortality in diabetic patients with end-stage renal disease is different in hemodialysis and peritoneal dialysis

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BACKGROUND AND HYPOTHESIS: There are diverse results in terms of the association between body mass index (BMI) and mortality risk in patients with end-stage renal disease (ESRD). The aim was to examine if there is an association between BMI and the risk of all-cause mortality in patients with diabetes mellitus (DM) and ESRD on hemodialysis (HD) or peritoneal dialysis (PD). METHODS: was used as the reference group. RESULTS: (HR0.65, CI0.49-0.85). In multivariate analyses, no associations between BMI and mortality risk were found in patients on PD. CONCLUSION: An increased risk of mortality in underweight DM patients on HD was found. Overweight, class 1 and class 2 obesity were associated with better survival in HD. KEY LEARNING POINTS: The association between BMI and risk of mortality is different in patients with DM on maintenance HD or PD. WHAT WAS KNOWN (MAXIMUM 50 WORDS): The association between BMI and risk of mortality in ESRD population on dialysis treatment is very divers and different study have shown different results. THIS STUDY ADDS (MAXIMUM 50 WORDS): High BMI associated with better survival in patients with diabetes and HD but this finding did not observed with PD. POTENTIAL IMPACT (ON PRACTICE OR UNDERSTANDING, MAXIMUM 50 WORDS): The importance to examine time-varying BMI frequently as independent covariance in patients with dialysis treatment.