Bioprosthetic valve degeneration is a rare complication in elderly intermediate-to-high risk patients undergoing TAVI, but is associated with increased mortality.
Cohort
No
What is the incidence and impact of bioprosthetic valve degeneration in elderly intermediate-to-high risk patients undergoing TAVI for native severe aortic stenosis?
In elderly intermediate-to-high risk patients undergoing TAVI, bioprosthetic valve degeneration is a rare complication but is associated with increased mortality.
p-value: p=0.0114
BACKGROUND/INTRODUCTION: Long-term data on hemodynamic performance and valve durability are essential to guide bioprosthetic valve selection and to safely expand transcatheter aortic valve implantation (TAVI) to lower-risk patients with severe aortic stenosis (AS). PURPOSE: This study aimed to assess the hemodynamic valve performance in a large cohort of patients undergoing TAVI with balloon-expandable (BEV) or self-expandable valves (SEV) and identify possible predictors of bioprosthetic valve degeneration (BVD). METHODS: All patients undergoing TAVI for native AS in a single centre between March 2008 and September 2023 underwent sequential echocardiographic follow-up at 30 days, 6 months and yearly thereafter. BVD was categorised as moderate or severe according to the Valve Academic Research Consortium 3 criteria. RESULTS: = 0.0114) were associated with an increased incidence of BVD. CONCLUSION: BVD is a rare complication in elderly intermediate-to-high risk patients undergoing TAVI. However, BVD is associated with increased mortality.
Meylaers et al. (Wed,) conducted a cohort in severe aortic stenosis. Transcatheter aortic valve implantation (TAVI) was evaluated on Bioprosthetic valve degeneration (BVD) (p=0.0114). Bioprosthetic valve degeneration is a rare complication in elderly intermediate-to-high risk patients undergoing TAVI, but is associated with increased mortality.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: