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May 14, 2026BMC AnesthesiologyOpen Access

Effects of epidural analgesia, regional blockade, and intravenous PCIA on early postoperative sleep disturbance and recovery outcomes after gastric and colorectal cancer surgery: a propensity score–based retrospective cohort study

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Authors

ZWZhaojun WuWenzhou Medical UniversityHWHejie WangWenzhou Hospital of Traditional Chinese MedicineYLYu LiHarbin University of Science and Technology

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Implication

Retrospective cohort study shows analgesic strategy influences sleep outcomes in cancer surgery, suggesting better approaches may improve recovery.

Key Points

  • This study aims to assess how different analgesic strategies affect early postoperative sleep disturbance and recovery in gastric and colorectal cancer surgery.
  • Retrospective cohort study of 860 patients undergoing gastric or colorectal cancer surgery
  • Patients received one of three postoperative analgesia methods: epidural analgesia, regional blockade, or intravenous PCIA
  • Outcomes analyzed included sleep disturbance, pain scores, opioids used, and recovery metrics using multivariable regression and propensity score methods.
  • Early postoperative sleep disturbance was reported in 55.3% of patients, with IV PCIA yielding the highest rates at 65.4% compared to 46.1% with epidural and 50.6% with regional blockade (P < 0.001)
  • Epidural analgesia and regional blockade were linked to lower odds of sleep disturbance compared to IV PCIA (adjusted OR 0.447 and 0.526, respectively, both P < 0.001)
  • Patients receiving epidural analgesia had a shorter length of stay compared to those with IV PCIA, approximately 0.9 days shorter.

Cite This Study

Wu et al. (2026) studied this question.

synapsesocial.com/papers/6a05659da550a87e60a1decehttps://doi.org/10.1186/s12871-026-03895-9
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Also Consider

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  1. 1Preemptive Versus Postoperative Analgesia in Colorectal Surgery: A Systematic Review and Meta‐Analysis2025 · 1 citations
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  5. 5Lateral quadratus lumborum block versus transversus abdominis plane block for perioperative analgesia in patients undergoing laparoscopic colorectal cancer surgery: a randomized, controlled clinical trial2025 · 2 citations