Key result
Cardiac computed tomography yielded significantly higher mean left ventricular ejection fraction (67.48% vs 63.64%) and end-diastolic volume compared to 2D transthoracic echocardiography.
Why the study?
To compare 2D transthoracic echocardiography and cardiac CT for evaluating left ventricular function, and to determine whether cardiac CT can serve as an alternative to TTE.
Does cardiac computed tomography provide comparable assessment of left ventricular functional parameters to 2D transthoracic echocardiography in patients with suspected coronary artery disease?
Observational (n=29)
No
Does cardiac computed tomography provide comparable assessment of left ventricular functional parameters to 2D transthoracic echocardiography in patients with suspected coronary artery disease?
Cardiac CT yields significantly higher ejection fraction and end-diastolic volume measurements compared to 2D TTE, indicating that these two imaging modalities should not be used interchangeably for left ventricular functional assessment.
Answers are grounded in this paper and cite their sources.
Cardiac CT yields higher EF and EDV than TTE; leaves open whether it can replace echocardiography for LV assessment.
Background and Aim：This study aimed to compare the results of 2D transthoracic echocardiography (TTE) and cardiac computed tomography (CT) in the evaluation of left ventricular function, and to determine the effectiveness of cardiac CT as well as whether it can serve as an alternative to TTE. Materials and Methods：A total of 29 patients who underwent cardiac CT for suspected coronary artery disease between June and August 2016 and also had TTE examinations were retrospectively analyzed. Measurements including ejection fraction (EF), end-diastolic volume (EDV), and end-systolic volume (ESV) were obtained using the modified Simpson method with both modalities. Results: The mean EF (67.48 ± 7.79%) and EDV (128.06 ± 28.34 mL) values obtained by CT were significantly higher than those measured by TTE (63.64 ± 3.86% and 98.45 ± 27.98 mL, respectively) (p=0.018 and p<0.001, respectively). No statistically significant difference was observed between the two methods in ESV measurements (TTE: 36.13 ± 12.90 mL; CT: 39.96 ± 14.57 mL; p=0.430). Conclusion: Although TTE remains the primary method for the evaluation of left ventricular function due to its accessibility, cardiac CT provides a valuable alternative by offering functional data, particularly in patients with limited acoustic windows.
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Ayşegül et al. (2026) conducted an observational in Suspected coronary artery disease (n=29). Cardiac computed tomography (CT) vs. 2D transthoracic echocardiography (TTE) was evaluated on Left ventricular ejection fraction (EF) (p=0.018). Cardiac computed tomography yielded significantly higher mean left ventricular ejection fraction (67.48% vs 63.64%) and end-diastolic volume compared to 2D transthoracic echocardiography.
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