Insilico and Invivo Pharmacological Evaluation of Impatiens Balsamina for Anti Depressant Activity

Impatiens balsamina is an annual herb, belongs to the family balsamaceous, commonly seen in India, China, Korea. it is an erect plant commonly known as rose balsam and garden balsam The plant is used in traditional medicines of Ayurveda, siddha. It is a sparsely-branched annual herbaceous plant and grow about 0.3 to 1 m tall. The leaves are about 4to12 cm long and 1.5 to 3cm wide. Flowers of the plant is used as dye in pastry. seeds of this plantare edible. Leaves and steam are also edible when boiled. leaves, steam, flowers are also having medicinal properties. Some of the pharmacological actions of the plant include (antimicrobial, anti-pruritic, anti-inflammatory, anti-depression. The study aims to screen compounds from ethanolic extract of impatiens balsamina (EEIB) by docking studies on potential targets of depression. The best test ligands were selected and molecular docking tests against the target protein (moa –a, moa –b, sert,) compared to that of control ligands present in the plant ofImpatiens balsamina (kaempferol, flavonoids, saponins, glycosides). Thepresentwork summarizes all the insilico and invivo work carried out on this plant in order to provide updated information for future work.