Potential fluorescent probe ethyl 3-(2-(1 H -benzo[ d ]imidazol-2-yl)-5 methoxynaphthalen-1-yl)propanoate for real-time monitoring of human serum albumin dynamics and cancer cell imaging

S. R. Roy; Pragya Trivedi; Titas Kumar Mukhopadhyay; Sapana Dubey; K. BAG; Sipra Ghosh; Subhojit Das; Subrata Mahanta; Tapas Das

doi:10.1039/d6nj00532b

January 1, 2026New Journal of Chemistry

Potential fluorescent probe ethyl 3-(2-(1 H -benzo[ d ]imidazol-2-yl)-5 methoxynaphthalen-1-yl)propanoate for real-time monitoring of human serum albumin dynamics and cancer cell imaging

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Key Points

This research aims to evaluate the effectiveness of EBINP as a fluorescent probe for monitoring human serum albumin and imaging cancer cells.
Investigated EBINP's interaction with native and SDS-denatured HSA.
Assessed EBINP's anticancer activity in breast cancer cells.
EBINP demonstrated strong compatibility with HSA, both native and denatured.
It showed moderate anticancer activity as a tracker for breast cancer cells.

Implication

Uncovers anticancer activity in breast cancer cells using a novel fluorescent probe, suggesting its potential as an imaging tool.

Abstract

EBINP acts as an extrinsic probe for native and SDS-denatured HSA, showing strong experimental–theoretical corroboration and moderate anticancer activity as a breast cancer cell tracker.

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Cite This Study

Roy et al. (2026) studied this question.

synapsesocial.com/papers/6a05677ca550a87e60a1f906 https://doi.org/10.1039/d6nj00532b

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Potential fluorescent probe ethyl 3-(2-(1 H -benzo[ d ]imidazol-2-yl)-5 methoxynaphthalen-1-yl)propanoate for real-time monitoring of human serum albumin dynamics and cancer cell imaging

Key Points

Implication

Abstract

Discussion

Cite This Study

Potential fluorescent probe ethyl 3-(2-(1 H -benzo[ d ]imidazol-2-yl)-5 methoxynaphthalen-1-yl)propanoate for real-time monitoring of human serum albumin dynamics and cancer cell imaging

Key Points

Implication

Abstract

Discussion

Cite This Study

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