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January 1, 2026Chemical ScienceOpen Access

Scaling up mechanochemical reactions: linking crystalline phase evolution studied via in situ PXRD with kinetics from MCR-ALS

Laura Macchietti Maria Carta Francesco Delogu Fabrizia Grepioni Franziska Emmerling Lucia Casali

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Key Points

The research aims to connect crystalline phase evolution with kinetic models to improve mechanochemical reaction scalability.
Utilized an in situ PXRD platform for real-time observation of phase changes.
Applied MCR-ALS for kinetic modeling of the mechanochemical processes.
Analyzed the evolution of crystalline phases during mechanochemical reactions.
Identified specific phase evolution patterns correlating with reaction kinetics.
Developed reliable kinetic models that support scalable mechanochemical processes.

Implication

Links phase evolution with kinetic models in mechanochemical reactions, suggesting enhanced scalability.

Abstract

The proposed in situ PXRD/MCR-ALS platform resolves complex phase evolution and derives kinetic models to advance mechanochemical scale up.

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Cite This Study

Macchietti et al. (2026) studied this question.

synapsesocial.com/papers/6a05684ea550a87e60a20b67 https://doi.org/10.1039/d6sc01158f

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