Voluntary overdose of 3000 mg of flecainide (20 tablets of 150 mg) triggered the development of Takotsubo syndrome in a 44-year-old woman.
Case Report (n=1)
Can flecainide toxicity trigger Takotsubo syndrome?
Flecainide toxicity may act as a potential trigger for the development of Takotsubo syndrome.
OBJECTIVE: Takotsubo syndrome, also known as stress cardiomyopathy, is predominantly reported in postmenopausal women and it is often triggered by a physical or emotional stressor. CASE REPORT: We present the case of a 44-year-old Caucasian woman admitted to the emergency department after voluntary intake of 20 tablets of flecainide 150 mg to commit suicide. During the in-hospital stay in the Cardiac Intensive Care Unit, the patient developed Takotsubo syndrome. CONCLUSIONS: The relative role of flecainide as a possible trigger of the syndrome is discussed in the context of the current literature evidence.
Moretti et al. (Tue,) conducted a case report in Takotsubo syndrome and flecainide toxicity (n=1). Flecainide was evaluated on Development of Takotsubo syndrome. Voluntary overdose of 3000 mg of flecainide (20 tablets of 150 mg) triggered the development of Takotsubo syndrome in a 44-year-old woman.