Key result
Pediatric cardiac tumor resection carries low mortality, but larger volume and transmural resection predict LV dysfunction.
Why the study?
Pediatric primary cardiac tumors are rare with poorly defined clinical features and prognoses, and the management of asymptomatic patients with cardiac fibromas remains controversial.
Cohort
No
Surgical resection of pediatric primary cardiac tumors can be performed with low mortality, though larger tumor volume index and transmural resection predict postoperative LV dysfunction.
Supports resection with low mortality in children; leaves open mitigation of LV dysfunction risk after large-volume or transmural procedures.
Background: Pediatric primary cardiac tumors (PCTs) are rare. Its clinical features and prognoses are not well defined. The management of asymptomatic patients with cardiac fibromas remains controversial. Objective: We aimed to examine our experience in surgical resection of pediatric PCT, with specific focuses on the management of large fibromas. Methods: This study included all the children who underwent surgical resection of PCT in our institution between December 2008 and June 2021. The last follow-up was performed between June 1st and August 26th, 2021. Kaplan-Meier method was used to estimate the postoperative survival, freedom from reoperation, event-free survival, and also related risk factors. The tumor volume and volume index (volume divided by body surface area) were measured for cardiac fibromas. Results: = 0.046) were risk factors for LV dysfunction following fibromas resection. Conclusion: Pediatric surgery for PCT can be performed with low mortalities and few adverse events. The size of cardiac fibroma in children relatively decreases with the increase of age. Larger tumor volume index than LV end-diastolic volume index and transmural tumor resection predicts postoperative LV dysfunction.
No takes yet. Share an insight, caveat, or question.
Qian et al. (2022) conducted a cohort in Pediatric primary cardiac tumors. Surgical resection was evaluated on Postoperative LV dysfunction (p=0.046). Surgical resection of pediatric primary cardiac tumors is associated with low mortality, while a larger tumor volume index and transmural resection predict postoperative LV dysfunction (P=0.046).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: