Key result
NAATs provide rapid and minimally invasive diagnosis for tuberculous pleural effusion.
Why the study?
Tools such as culture and pleural biopsy have limitations including low sensitivity, long turnaround time, and invasiveness, making nucleic acid amplification tests a rapid, minimally invasive alternative.
What is the diagnostic accuracy of nucleic acid amplification tests for tuberculous pleural effusion?
What is the diagnostic accuracy of nucleic acid amplification tests for tuberculous pleural effusion?
NAATs offer a rapid and minimally invasive alternative to culture and pleural biopsy for diagnosing tuberculous pleural effusion.
) culture and pleural biopsy. These tools have limitations, including low sensitivity, long turnaround time and invasiveness. The nucleic acid amplification test (NAAT) is a rapid and minimally invasive tool for diagnosing TPE. This review summarizes the diagnostic accuracy of available NAATs for TPE, with a focus on the evidence from systematic reviews and meta-analyses. The NAATs summarized in this review include in-house NAATs, GeneXpert-MTB/RIF, GeneXpert-MTB/RIF Ultra, simultaneous amplification and testing-tuberculosis, FluoroType MTB and loop-mediated isothermal amplification.
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Wen et al. (2023) conducted a review in Tuberculous Pleural Effusion. Nucleic Acid Amplification Tests (NAATs) vs. Culture and pleural biopsy was evaluated on Diagnostic accuracy. Nucleic acid amplification tests (NAATs) serve as rapid and minimally invasive tools for diagnosing tuberculous pleural effusion, with diagnostic accuracy summarized from systematic reviews.
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