Coronary Thrombosis

Article1 August 1965Coronary ThrombosisIts Mechanism and Possible Prevention by Linolenic AcidP. A. OWREN, M.D.P. A. OWREN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-63-2-167 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptThe rapid increase in the prevalence of coronary heart disease (CHD) in recent decades has frightened the public, alarmed the health authorities, and challenged the medical profession. The fundamental lesion in more than 95% of all cases of CHD is coronary atherosclerosis. This is always a local manifestation of a generalized disease, a universal process that occurs in most humans. It begins in early childhood as fatty streaks and develops into progressive atheroma from the time of adolescence (Figure 1). 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Owren, M.D., Rikshospitalet, Medisinsk Avdeling A, Universitetsklinikk, Oslo, Norway. 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AtherosclerosisLINOLENIC ACID AND CORONARY THROMBOSISP. A. OWREN, M.D.PSEUDOMOSAICISM IN MALES WITH MILD GLUCOSE-6-PHOSPHATE-DEHYDROGENASE DEFICIENCYLINOLENIC ACID AND PLATELET ADHESIVENESS 1 August 1965Volume 63, Issue 2Page: 167-184KeywordsAtheromasAtherosclerosisCongenital heart diseaseCoronary heart diseaseFamilial hypercholesterolemiaIngestionLesionsPrevention, policy, and public healthStable coronary artery diseaseThrombosis ePublished: 1 December 2008 Issue Published: 1 August 1965 Copyright & PermissionsCopyright ©, 1965, by The American College of PhysiciansPDF downloadLoading ...