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January 1, 2026Open Access

A scalable automated framework for validating antibody-antigen recognition through thermal stability

Aline Albuquerque Júlia Souza Diego Almeida João Raimundo dos Santos Silva Júnior

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Key Points

To develop a scalable framework that automates the validation process of antibody-antigen recognition through thermal stability.
Proposed an automated system for assessing antibody-antigen interactions using thermal stability measurements.
Framework designed to be scalable for extensive validation tasks.
Utilized methods pertinent to immunobiologicals for validation processes.
Successfully demonstrated the framework's ability to validate antibody-antigen recognition reliably.
Achieved high accuracy in assessing thermal stability for various antibody-antigen pairs.

Implication

Framework validates antibody-antigen recognition in immunobiologicals, suggesting efficient application in research.

Abstract

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Cite This Study

Albuquerque et al. (2026) studied this question.

synapsesocial.com/papers/6a06b74ce7dec685947aa3d1 https://doi.org/10.35259/isi.2026_76286

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