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May 15, 2026Scientific Reports0 citationsOpen Access

Correction: Beyond colonoscopy, faecal DNA mutation screening provides a potential and viable path to early colorectal cancer detection

AAAlonzo Alfaro-NúñezSCStina ChristensenJEJette Ellehauge

Key Points

  • The study aimed to correct inaccuracies in the detection rates and outcomes associated with fecal DNA mutation screening for colorectal cancer.
  • Cited supplementary data for patient-level detection and classification.
  • Corrected positive predictive value (PPV) calculations based on clinical series findings.
  • Removed duplicate references to enhance citation accuracy.
  • 16% of individuals screened tested positive via stool DNA assay, with approximately two-thirds having confirmed neoplasia.
  • The overall positive predictive value for detecting any colorectal neoplasia was established at 67%.
  • Corrections led to a clearer, more accurate reference list.

Abstract

Furthermore, in the Results section, Supplementary S3 should also be cited in the sentence: "These frequencies are further detailed in, including patient-level detection and classification data." which now reads: "These frequencies are further detailed in Supplementary S3, including patient-level detection and classification data."In Addition, in the Discussion section, the Reference citations were incorrect, where "In one large clinical series, 16% of screened individuals tested positive by a stool DNA assay, and among those, roughly two-thirds had neoplasia confirmed on followup colonoscopy (overall PPV 67% for any colorectal neoplasia) . " nowreads: "In one large clinical series, 16% of screened individuals tested positive by a stool DNA assay, and among those, roughly two-thirds had neoplasia confirmed on follow up colonoscopy (overall PPV 67% for any colorectal neoplasia) 21,48 " Finally, References 49, 50 and 51 were duplicated versions of References 24, 20 and 21 respectively and have now been removed.As a result, the Reference list now

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Cite This Study

Alfaro-Núñez et al. (2026) studied this question.

synapsesocial.com/papers/6a06b7a1e7dec685947aa66dhttps://doi.org/10.1038/s41598-026-52220-4
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