PRENATAL AND POSTNATAL OUTCOMES OF FOETAL MEGACYSTIS: What to expect when posterior urethral valves are excluded? A retrospective multicentre study.

C. Rochet-Capellan; B. Tulelli; J. Massardier; A. Fichez; M. Massoud; J. Teoli; D. Demède; V. Bidault

doi:10.1016/j.jpurol.2026.106005

May 1, 2026Journal of Pediatric UrologyOpen Access

PRENATAL AND POSTNATAL OUTCOMES OF FOETAL MEGACYSTIS: What to expect when posterior urethral valves are excluded? A retrospective multicentre study.

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Key Points

This study aims to describe the long-term outcomes of foetal megacystis cases excluding posterior urethral valves.
Conducted as a retrospective multicentre study between 2009 and 2023
Included pregnant women referred for suspected foetal megacystis across three units
Excluded cases confirmed with posterior urethral valves and collected comprehensive maternal and foetal data.
Among 96 confirmed cases, 31 (32.3%) resulted in live births, while 49 (51%) were medical terminations and 16 (16.7%) involved intrauterine foetal deaths
Earlier gestational diagnosis was linked to poor outcomes (p < 0.001)
In live-born males, 34.6% exhibited urinary issues, particularly vesicoureteral reflux associated with third trimester dilatation (p = 0.047).

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Implication

Retrospective multicentre study reports outcomes of foetal megacystis excluding posterior urethral valves, highlighting significant implications for prenatal counselling.

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Rochet-Capellan et al. (2026) studied this question.

synapsesocial.com/papers/6a06b7eae7dec685947aa774 https://doi.org/10.1016/j.jpurol.2026.106005

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PRENATAL AND POSTNATAL OUTCOMES OF FOETAL MEGACYSTIS: What to expect when posterior urethral valves are excluded? A retrospective multicentre study.

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PRENATAL AND POSTNATAL OUTCOMES OF FOETAL MEGACYSTIS: What to expect when posterior urethral valves are excluded? A retrospective multicentre study.

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