The field of inorganic chemistry is significantly broadened by coordination compounds, which are known for their exceptional versatility. In recent years, the importance of coordination chemistry has grown due to its vital role in industrial processes, host-guest supra molecular systems, and the development of new pharmaceuticals. The existence of a vast array of organic and inorganic ligands allows for the synthesis of numerous complexes with various metal ions under diverse conditions. Particularly, Schiff base ligands have become a focal point of interest for contemporary chemists due to their unique properties.l. Schiff base transition metal complexes are foundational to both chemical and biochemical research. As a significant class of organic ligands, they readily coordinate with diverse metal centers to produce industrially relevant homogeneous catalysts 2-4. These chiral complexes exhibit exceptional selectivity across a range of chemical processes, including the formation of epoxies, various oxidation, and hydroxylation reactions. These complexes are also biologically active and are widely used as drugs such as antiviral 5, antifungal 6, antibacterial 7 and antidiabetic 8. The complexes of Schiff bases are also used in cancer treatment 9. Due to the dual nature of the mine group—where carbon acts as an electrified and nitrogen as a nucleophile—these ligands bind easily to biological targets. This interaction is key to inhibiting enzymatic pathways or disrupting DNA synthesis, while also serving as a tool for diagnostic imaging in MRI
Satyam Kumar (Wed,) studied this question.
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