Observational data reveal that heart failure and pleural effusion may signal early systemic lupus erythematosus, indicating essential early intervention.
Heart failure and unilateral pleural effusion may rarely represent initial manifestations of SLE in adults. Diagnostic evaluation is often challenging due to overlap with common conditions such as congestive heart failure. Early recognition and timely management are crucial for preventing disease progression and achieving optimal clinical outcomes.
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Rijal et al. (2026) studied this question.
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