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January 9, 2020Nature CommunicationsOpen Access

GM-CSF drives dysregulated hematopoietic stem cell activity and pathogenic extramedullary myelopoiesis in experimental spondyloarthritis

Daniel Regan-Komito James W. Swann Philippos Demetriou E. Suzanne Cohen Nicole J. Horwood Stephen N. Sansom Thibault Griseri

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Abstract

T cells and innate lymphoid cells, mast cells are a source of GM-CSF in this model, and its pathogenic production is promoted by the alarmin IL-33.

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Regan-Komito et al. (2020) studied this question.

synapsesocial.com/papers/6a06f328616fd0436a842364 https://doi.org/10.1038/s41467-019-13853-4

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