Why the study?
Does orthostatic hypotension predict 4-year all-cause mortality in elderly Japanese American men?
Population
3522 Japanese American men 71 to 93 years old from the Honolulu Heart Program
Comparison
Orthostatic hypotension vs No orthostatic hypotension
Design
Cohort
Follow-up
4 years
Key result
Orthostatic hypotension was a significant independent predictor of 4-year all-cause mortality in elderly ambulatory men (RR 1.64; 95% CI 1.19-2.26).
Authors
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May flag higher mortality risk in elderly men; hypothesis-generating as frailty marker, needing prospective validation before clinical use.
Cohort (n=3,522)
Does orthostatic hypotension predict 4-year all-cause mortality in elderly Japanese American men?
Orthostatic hypotension is an independent predictor of 4-year all-cause mortality in elderly ambulatory men, suggesting it may serve as a marker for physical frailty.
Effect estimate: RR 1.64 (95% CI 1.19 to 2.26)
Absolute Event Rate: 56.6% vs 38.6%
Masaki et al. (1998) conducted a cohort in Orthostatic hypotension (n=3,522). Orthostatic hypotension vs. No orthostatic hypotension was evaluated on 4-year all-cause mortality (RR 1.64, 95% CI 1.19 to 2.26). Orthostatic hypotension was a significant independent predictor of 4-year all-cause mortality in elderly ambulatory men (RR 1.64; 95% CI 1.19-2.26).