Why the study?
The POLAR cryoballoon system features design characteristics intended to improve maneuvering in difficult anatomies, but its lesion profiles, touch-up ablation rates, and anatomical predictors compared with Arctic Front Advance Pro were unclear.
Does the POLAR cryoballoon system reduce the touch-up radiofrequency ablation rate compared to the AFA-Pro system in patients undergoing first cryoballoon ablation for paroxysmal atrial fibrillation?
Does the POLAR cryoballoon system reduce the touch-up radiofrequency ablation rate compared to the AFA-Pro system in patients undergoing first cryoballoon ablation for paroxysmal atrial fibrillation?
The POLAR cryoballoon system may reduce the need for touch-up radiofrequency ablation in the right inferior pulmonary vein compared to the AFA-Pro system, particularly in patients with challenging anatomies.
May favor POLAR for challenging RIPV anatomies; leaves open confirmation in randomized trials before practice change.
Background: A new technology, the POLAR cryoballoon system, was designed to enhance maneuvering and stabilizing catheter positions with a softer balloon and more deflectable sheath. These novel characteristics may help achieve successful pulmonary vein (PV) isolation in difficult cases when conventional balloons were used. Objective: This study aimed to investigate the differences in the lesion profiles, touch-up radiofrequency ablation (RFA) rate, and anatomical predictors of acute PV isolation between the POLAR and Arctic Front Advance Pro (AFA-Pro). Methods: This retrospective study included 338 consecutive patients who underwent a first cryoballoon ablation for paroxysmal atrial fibrillation at Keio University Hospital from April 2019 to September 2023. Using propensity score matching, we extracted 135 pairs treated with a POLAR or AFA-Pro, compared the procedural outcomes, and explored the anatomical predictors related to successful PV isolations. Conclusion: The touch-up RFA rate for the RIPV was significantly lower in the POLAR group than in the AFA-Pro group, with a particularly pronounced difference for inferiorly oriented RIPVs.
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Yamashita et al. (2025) studied this question.
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