(8) motif. Further N-H...O and O-H...O hydrogen bonds help to stabilize the crystal packing, along with aromatic π-π stacking interactions in I and carbonyl...π interactions in II. The Hirshfeld surface analysis and fingerprint plots reveal that O...H/H...O interactions contribute 34.4% of the total interactions in the crystal packing of cocrystal I and 36.7% in salt II.
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Ram et al. (2022) studied this question.
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