Answers are grounded in this paper and cite their sources.
(isradipine), iron (deferiprone), and extracellular α-synuclein (passive immunization), and upcoming trials of interventions affecting c-Abl, glucagon-like peptide-1, and glucocerebrosidase, it might be argued that further trials in populations not enriched for the targeted pathogenic process are doomed to repeat the failures of the past.
No takes yet. Share an insight, caveat, or question.
Lang et al. (2018) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: