Key result
Prostate carcinoma presents as pulmonary tumor thrombotic microangiopathy driven by adenocarcinoma cells embolizing small arteries.
Case Report (n=1)
No
This case report highlights the clinical and pathological findings of pulmonary tumor thrombotic microangiopathy (PTTM) caused by prostate carcinoma.
PTTM from prostate carcinoma remains rare; extends sparse case reports but leaves management questions open.
Pulmonary tumor thrombotic microangiopathy (PTTM) is a fatal malignancy-related condition that involves rapidly progressing hypoxia and pulmonary hypertension. We report a case of PTTM caused by prostate carcinoma, which was diagnosed before autopsy in an 81-year-old man. Computed tomography showed diffuse ground-glass opacities, consolidation, and small nodules in the peripheral regions of the lung. Autopsy showed adenocarcinoma cells embolizing small pulmonary arteries with fibrocellular intimal proliferation, which was consistent with PTTM caused by prostate carcinoma.
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Katayama et al. (2016) conducted a case report in Pulmonary tumor thrombotic microangiopathy (PTTM) caused by prostate carcinoma (n=1). An 81-year-old man was diagnosed with pulmonary tumor thrombotic microangiopathy caused by prostate carcinoma, confirmed by autopsy showing adenocarcinoma cells embolizing small pulmonary arteries.
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