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August 1, 2002Journal of Cardiovascular Electrophysiology184 citations

Cerebrovascular Complication Associated with Pulmonary Vein Ablation

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LKLai Chow KokJMJ. Michael MangrumDHDavid E. Haines

Key Result

Radiofrequency ablation for a focal source of atrial fibrillation was associated with a 5% rate of cerebrovascular events, with higher risk in patients with prior transient ischemic attack.

Study Design

Type

Observational (n=56)

Structured PICO

Does radiofrequency ablation cause cerebrovascular events in patients with paroxysmal atrial fibrillation?

P
Population
56 patients with paroxysmal atrial fibrillation undergoing radiofrequency ablation for a focal source of AF.
I
Intervention
Radiofrequency (RF) catheter ablation
O
Outcome
Cerebrovascular eventsafety

Radiofrequency ablation for paroxysmal atrial fibrillation carries a risk of cerebrovascular complications, which may be higher in older patients with a history of transient ischemic attacks.

Abstract

INTRODUCTION: Radiofrequency (RF) ablation has become an established treatment modality for patients with paroxysmal atrial fibrillation (AF). A principal limitation of RF catheter ablation is the risk of thromboembolism. Stroke as a complication after ablation of triggers of AF has not been previously reported. METHODS AND RESULTS: Fifty-six patients underwent RF ablation for a focal source of AF. Forty-nine patients (86%) had AF triggers in > or = 1 pulmonary vein. Mean procedure time was 227 +/- 74 minutes. Cerebrovascular event occurred in 3 (5%) patients, all >60 years old. Two of the three patients had a prior history of transient ischemic attacks. CONCLUSION: The risk of stroke from RF ablation may be higher in paroxysmal AF patients with prior transient ischemic attack.

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Cite This Study

Kok et al. (2002) conducted an observational in paroxysmal atrial fibrillation (n=56). Radiofrequency (RF) ablation was evaluated on Cerebrovascular event. Radiofrequency ablation for a focal source of atrial fibrillation was associated with a 5% rate of cerebrovascular events, with higher risk in patients with prior transient ischemic attack.

synapsesocial.com/papers/6a07b40244ff8ad339f69a79https://doi.org/10.1046/j.1540-8167.2002.00764.x
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