Key result
The death of a significant person was associated with a 21.1-fold increased incidence rate of acute myocardial infarction within 24 hours (95% CI 13.1-34.1).
Why the study?
Does the death of a significant person acutely increase the risk of acute myocardial infarction?
Population
1,985 participants interviewed during index hospitalization for an acute myocardial infarction between 1989…
Comparison
Death of a significant person in the days… vs Each patient's own control information, defined…
Design
Case-control
Authors
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Bereavement may heighten acute MI risk; leaves open whether support interventions mitigate events.
Observational (n=1,985)
Yes
Does the death of a significant person acutely increase the risk of acute myocardial infarction?
Effect estimate: Rate ratio 21.1 (95% CI 13.1-34.1)
Intense grief over the death of a significant person is associated with a 21.1-fold acutely increased risk of myocardial infarction within 24 hours.
Mostofsky et al. (2012) conducted an observational in Acute myocardial infarction (n=1,985). Death of a significant person vs. Control period 1 to 6 months before infarction was evaluated on Incidence rate of acute MI onset (Rate ratio 21.1, 95% CI 13.1-34.1). The death of a significant person was associated with a 21.1-fold increased incidence rate of acute myocardial infarction within 24 hours (95% CI 13.1-34.1).
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