Key result
Functional left ventricular aneurysms had a significantly larger volume as a fraction of global end-diastolic volume compared to true aneurysms (24.4±10.6% vs 13.2±8.5%, p=0.01).
Why the study?
Can quantitative angiographic variables describe the morphological characteristics of functional versus true left ventricular aneurysms?
Observational (n=33)
Can quantitative angiographic variables describe the morphological characteristics of functional versus true left ventricular aneurysms?
Quantitative angiographic analysis reveals that functional left ventricular aneurysms have a larger fractional volume and more circular end-systolic shape compared to true aneurysms.
May aid angiographic differentiation of functional vs true aneurysms post-MI; leaves open validation for prognosis or management.
Thirty-three 30 degrees RAO left-ventricular angiograms with postinfarction aneurysms were analyzed to determine whether some quantitative variables could describe their morphological characteristics. Seventeen aneurysms were classified as functional (localized without a clear neck), and 16 as true (with a saccular shape). Left-ventricular volumes and global ejection fractions did not differ between the two types. The volume of functional aneurysms as a fraction of global end-diastolic volume was significantly larger (24.4+or-10.6% versus 13.2+or-8.5%, p=0.01). The end-systolic shape of ventricles with a functional aneurysm was more circular (77+or-6 versus 71+or-7, p<0.05) and showed a significantly smoother transition between contractile and noncontractile regions in the anterior site. The anatomic characteristics of resected areas in operated patients were similar in the two types of aneurysms.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">></ETX>
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Vassanelli et al. (2003) conducted an observational in Postinfarction left ventricular aneurysms (n=33). Functional aneurysms vs. True aneurysms was evaluated on Volume of aneurysm as a fraction of global end-diastolic volume (p=0.01). Functional left ventricular aneurysms had a significantly larger volume as a fraction of global end-diastolic volume compared to true aneurysms (24.4±10.6% vs 13.2±8.5%, p=0.01).
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