Key result
Higher physical activity is linked to increased HRV regardless of insulin resistance.
Why the study?
Autonomic activity is possibly influenced by physical activity, but whether this association is modified by insulin resistance remains unclear.
Does physical activity improve heart rate variability and is this association modified by insulin resistance in adults aged 30-79 years?
Cross-Sectional (n=2,016)
Does physical activity improve heart rate variability and is this association modified by insulin resistance in adults aged 30-79 years?
Higher physical activity is associated with improved parasympathetic modulation (higher HRV and lower HR), an effect that is independent of insulin resistance.
Higher physical activity was associated with better HRV independent of insulin resistance; leaves open prospective effects on autonomic function.
BACKGROUND: Autonomic activity is possibly influenced by physical activity (PA). However, it remains unclear whether this association is modified by insulin resistance. METHODS: This population-based study between 2009 and 2012 included 2016 men and women aged 30-79 years. The PA was assessed using a validated questionnaire based on sleep, occupation, transportation, household characteristics, and leisure-time PA. Heart rate (HR) and heart rate variability (HRV) in the sitting position were determined from 5-minute recordings of pulse waves detected by a fingertip sensor. The HRV was calculated as frequency (standard deviation of normal-to-normal [NN] intervals [SDNN]), root mean square of successive differences (RMSSD), and percentage differences between normal NN intervals >50 milliseconds [pNN50]) and time domains. Insulin resistance was evaluated using the homeostasis model assessment index (HOMA-IR). RESULTS: HR, RMSSD, and pNN50 were related to the total and moderate/vigorous PA tertiles in models that included HOMA-IR. The partial regression coefficient of total PA per 1-SD increase was .05 (P = .019) for log-transformed RMSSD and 1.86 (P = .001) for pNN50. No interactive associations were observed between PA and HOMA-IR. CONCLUSIONS: Low total PA was associated with increased HR and low levels of RMSSD and pNN50, reflecting parasympathetic modulation that was not modified by insulin resistance.
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Saito et al. (2020) reported a cross-sectional. Physical activity was evaluated on Heart rate and heart rate variability (SDNN, RMSSD, pNN50) (Partial regression coefficient 0.05 for log-RMSSD; 1.86 for pNN50, p=0.019 for log-RMSSD; 0.001 for pNN50). Higher total physical activity was associated with increased heart rate variability (partial regression coefficient 0.05 for log-RMSSD, P=0.019), which was not modified by insulin resistance.
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