Reveals targeting FAP may slow abdominal aortic aneurysm progression, suggesting a novel therapeutic approach.
F-FAP inhibitor PET/CT imaging in an infectious AAA patient revealed strong FAP expression in the aneurysm wall. These findings underscore the importance of the PDGF-BB/EGR1/FAP axis in AAA pathogenesis and suggest that targeting FAP could offer therapeutic potential for managing AAA progression.
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Zhou et al. (2025) studied this question.
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