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Protein chains are usually folded into one or several discrete globular units called domains (Schulz α-proteins which are mainly α-helical, β-proteins which contain antiparallel β-strands and α/β proteins which have a central core consisting of a sheet of strands, most of which are parallel. The connexions between the parallel strands in αβ-proteins frequently contain helices which are packed on both sides of the sheet in a regular way (Chothia, Levitt & Richardson, 1977).
Carl‐Ivar Brändén (Fri,) studied this question.
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