May 18, 2004Circulation
Intraprocedural Stent Thrombosis During Implantation of Sirolimus-Eluting Stents
Key result
Total stent length per vessel was significantly associated with intraprocedural stent thrombosis during sirolimus-eluting stent implantation (OR 1.03; 95% CI 1.011-1.046; P=0.0028).
Why the study?
Is total stent length associated with the occurrence of intraprocedural stent thrombosis during sirolimus-eluting stent implantation?
Population
670 patients with 1362 lesions undergoing elective implantation of sirolimus-eluting stents
Design
Cohort
Follow-up
intraprocedural
Authors
Discussion
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Member takes
Implication
Supports caution with longer stent lengths during sirolimus-eluting stent implantation; leaves open whether minimization improves outcomes.
Study Design
Type
Observational (n=670)
Multicenter
Yes
Structured PICO
Is total stent length associated with the occurrence of intraprocedural stent thrombosis during sirolimus-eluting stent implantation?
P
Population
670 patients with 1362 lesions undergoing elective implantation of sirolimus-eluting stents
I
Intervention
Sirolimus-eluting stent implantation
O
Outcome
Occurrence of intraprocedural stent thrombosis (IPST)safety
Main Result
Effect estimate: OR 1.03 (95% CI 1.011 to 1.046)
p-value: p=0.0028
Total stent length is significantly associated with the rare but serious complication of intraprocedural stent thrombosis during elective sirolimus-eluting stent implantation.
Cite This Study
Chieffo et al. (2004) conducted an observational in Coronary artery disease requiring stent implantation (n=670). Sirolimus-eluting stent implantation (Cypher) was evaluated on Intraprocedural stent thrombosis (IPST) (OR 1.03, 95% CI 1.011 to 1.046, p=0.0028). Total stent length per vessel was significantly associated with intraprocedural stent thrombosis during sirolimus-eluting stent implantation (OR 1.03; 95% CI 1.011-1.046; P=0.0028).