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May 16, 2026Discover OncologyOpen Access

Novel cuproptosis related long non-coding RNA signature in oral squamous cell carcinoma prognosis and immunotherapy

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Authors

SSSubhayan Sur

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Overview

Randomized trial reveals cuproptosis-related lncRNA impacts prognosis and immunotherapy in OSCC, suggesting a new approach for treatment.

Key Points

  • To develop a novel prognostic signature based on cuproptosis-related lncRNAs for patients with oral squamous cell carcinoma.
  • Developed a four-lncRNA prognostic signature for OSCC patients.
  • Stratified patients based on immune microenvironment patterns.
  • Experimental validation of STARD4-AS1 for biological relevance.
  • Identified distinct immune microenvironment patterns in OSCC patients.
  • Enhanced prognostic accuracy through lncRNA profiling with cuproptosis relevance.
  • Supported the integration of cuproptosis biology with clinical prognostic strategies.

Cite This Study

Subhayan Sur (2026) studied this question.

synapsesocial.com/papers/6a080985a487c87a6a40b63fhttps://doi.org/10.1007/s12672-026-05171-1
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Also Consider

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  1. 1Cuproptosis in cancer: biological implications and therapeutic opportunities2024 · 66 citations
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  4. 4A Narrative Review on Oral Squamous Cell Carcinoma2025 · 12 citations