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May 16, 2026Scripta MedicaOpen Access

Case series of Burkholderia pseudomallei infections in critically ill patients: Unveiling key challenges

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Authors

RRRishwanth RajaBSBaby SailajaRHR.V. Hemalatha

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Overview

Case series reveals melioidosis diagnostic challenges and treatment responses in diabetic patients, indicating need for prompt recognition.

Key Points

  • This study aims to highlight the diagnostic challenges and diverse clinical presentations of melioidosis in critically ill patients.
  • Presented a case series of seven diabetic individuals with Burkholderia pseudomallei infections from an endemic area.
  • Achieved laboratory confirmation through culture and nested polymerase chain reaction (PCR).
  • Administered appropriate intravenous therapy followed by oral antibiotics.
  • Most patients improved with appropriate treatment; however, one individual experienced a recurrence.
  • The varied presentations of melioidosis often mimic other endemic infections, resulting in delayed diagnoses.
  • Emphasized the importance of early clinical recognition and the use of molecular tools for better patient outcomes.

Cite This Study

Raja et al. (2026) studied this question.

synapsesocial.com/papers/6a080985a487c87a6a40b6c5https://doi.org/10.5937/scriptamed57-60050
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Diagnostic and therapeutic challenges in melioidosis: a case series from South India2026
  2. 2Melioidosis: diverse clinical manifestations and patient outcomes in a case series2026
  3. 3Diagnosis and treatment of severe acute sepsis caused by Burkholderia pseudomallei infection: a case report and literature review2025
  4. 4Clinical Presentations of Melioidosis and Antibiogram of Burkholderia pseudomallei: An 8-year Study in a Tertiary Care Center, South India2024 · 1 citations
  5. 5Melioidosis at a Tertiary Care Center in Jaipur, India: Diagnostic Challenges and Therapeutic Insights2025