Long-Term Outcomes of a Multicenter Aspirin Deprescribing Intervention

Figures

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  Figure.. Scatterplot of Patients Taking Warfarin and Aspirin Concomitantly Discontinuing Aspirin and/or Having a Bleeding Event per Month, Before and After the Intervention The average monthly deprescribing for aspirin was 0.95% before the intervention and 2.66% after the intervention (P < .001). Of note, the plot only shows the first time aspirin was discontinued per patient. Once aspirin was discontinued, that patient was excluded from the population in subsequent months. Bleeding events were significantly lower after the intervention vs before it. However, an increasing trend in bleeding event rates over time was observed in the postintervention period. The P values reflect the comparison of the before vs after intervention monthly bleeding event rate slopes (P = .001) and means respectively (P < .001).