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May 16, 2026Applied SciencesOpen Access

Multi-Element Ion Release from Stainless Steel and Nickel–Titanium Orthodontic Archwires in Neutral and Fluoride-Containing Artificial Saliva: A Factorial In Vitro ICP-OES Study

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Authors

MMMarcin MikulewiczEKEdward KijakKSKatarzyna Skośkiewicz-Malinowska

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Overview

In vitro study quantifies ion release from orthodontic archwires in saliva, suggesting material selection considerations for nickel-sensitive patients.

Key Points

  • The study aims to assess the release of metal ions from orthodontic archwires in different saliva conditions and evaluate the influence of manufacturers.
  • Non-parametric tests were used to analyze ion release quantified by ICP-OES from four manufacturers' archwires immersed in neutral and fluoride-containing artificial saliva.
  • Archwires tested included stainless steel (SS) and nickel-titanium (NiTi) varieties, measured over 35 days at six time points.
  • NiTi archwires released significantly more nickel than SS in fluoride saliva (p = 0.029).
  • American Orthodontics NiTi released more nickel than Dentaurum and Ormco (p = 0.005).
  • Ormco SS released three times more iron compared to other SS wires (p = 0.003).

Cite This Study

Mikulewicz et al. (2026) studied this question.

synapsesocial.com/papers/6a080a71a487c87a6a40c5c5https://doi.org/10.3390/app16104778
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