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Review examines the psychological and biological interactions in food allergy, suggesting improved outcomes through integrated care.
Food allergy is a chronic immune-mediated condition that must be understood not only as a biological disorder but also as a biopsychosocial condition with significant psychological and neurodevelopmental consequences. Beyond the management of acute allergic reactions, individuals living with food allergy experience ongoing threat appraisal, dietary restriction, and social constraints, shaping emotional regulation, cognition, and wellbeing. This review adopts a psychology-led biopsychosocial and neuropsychological framework to examine the mechanisms through which immune activation and food avoidance influence psychological functioning. Drawing on medical psychology, psychoneuroimmunology, and gut–brain research, we explore how threat perception, interoceptive awareness, learning processes, stress physiology, and family context interact to shape emotional and behavioural responses to food allergy. Particular attention is given to the role of risk perception, vigilance, and learned avoidance in driving anxiety and reduced quality of life. By integrating evidence across psychological and biological domains, this review argues for a more comprehensive model of food allergy that recognises the cumulative emotional and neuropsychological burden associated with living with chronic dietary risk. Greater integration of psychological perspectives within allergy care may help support adaptive coping, reduce unnecessary restriction, and improve quality-of-life outcomes for individuals and families affected by food allergy.
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Audrey Dunn Galvin (2026) studied this question.
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