Key result
Transesophageal and intracardiac echocardiography provided additional diagnostic information on small, focal structural abnormalities in patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy compared to standard transthoracic echocardiography.
Why the study?
Two-dimensional echocardiography can skip regional localized right ventricular wall anomalies in ARVD/C, prompting evaluation of transesophageal and intracardiac ultrasound for additional diagnostic information.
Do transesophageal and intracardiac ultrasound improve the detection of right ventricular structural abnormalities compared to transthoracic echocardiography in patients with ARVD/C?
Case Report (n=2)
No
Do transesophageal and intracardiac ultrasound improve the detection of right ventricular structural abnormalities compared to transthoracic echocardiography in patients with ARVD/C?
Answers are grounded in this paper and cite their sources.
Transesophageal and intracardiac echocardiography can detect subtle structural abnormalities in ARVD/C, such as localized aneurysms and loss of trabeculations, which may be missed by standard transthoracic echocardiography.
RATIONALE: Two-dimensional echocardiography (2D echo) is a major tool for the diagnosis of Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C). However 2D echo can skip regional localized anomalies of the right ventricular wall. We aimed to determine whether transesophageal and intracardiac ultrasound can provide additional information, on the right ventricular abnormalities compared to 2D echo. PATIENT CONCERNS: Case 1 is a 30-year-old patient that presented in the Emergency Department with multiple episodes of fast monomorphic ventricular tachycardia (VT) manifested by palpitations and diziness. Case 2 is a 65-year-old patient that also presented with episodes of ventircular tachycardia associated with low blood pressure. DIAGNOSIS: Both patients had a clear diagnosis of arrhythmogenic right ventricular dysplasia/cardiomyopathy confirmed by cardiac magnetic resonance imaging. INTERVENTION: In both patients transesophageal and intracardiac ultrasound was performed, which brought more information on the diagnosis of ARVD/C compared to transthoracic echocardiograpy. OUTCOMES: The first patient was implanted with an internal cardiac defibrillator and treated with Sotalol for VT recurrences. He presented episodes of VT during follow-up, treated with antitachycardia pacing. The second patient was implanted with an internal cardiac defibrillator and treated with Sotalol without any VT recurrence at 18 month-follow-up. LESSONS: Transesophageal echocardiography and intracardiac echocardiography can provide additional information on small, focal structural abnormalities in patients with ARVD/C: bulges, saculations, aneurysms with or without associated thrombus, partial or complete loss of trabeculations and hypertrophy of the moderator band. These changes are particularly important in cases with "concealed" form of the disease in which no morphological abnormalities are evident in transthoracic echocardiograpy.
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Cismaru et al. (2020) conducted a case report in Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C) (n=2). Transesophageal echocardiography (TEE) and intracardiac echocardiography (ICE) vs. Transthoracic echocardiography (TTE) was evaluated on Detection of right ventricular structural abnormalities. Transesophageal and intracardiac echocardiography provided additional diagnostic information on small, focal structural abnormalities in patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy compared to standard transthoracic echocardiography.
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