Identification of Biomarkers of Arrhythmogenic Cardiomyopathy (ACM) by Plasma Proteomics

Figures

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  Figure 1. Protein profiles obtained by 2DE pH 3-10. The figures (A–D) are for the gel proteins profiles (A) Gel A Protein profile of female control (TF), (B) Gel B Protein profile of patient A2, the arrow 2 represent LMNA, (C) Gel C Protein profiles of patient A8, the arrow 1 represented PKP2; the arrow 2 represent LMNA and the arrow 6 represent TMEM43, (D) Gel D Protein profiles of patient A9; the arrow 1 represent PKP2 and the arrow 6 represent TMEM43). The arrow numbers 1, 2, 3, 4, 5, and 6 represent the proteins: 1: PKP2, 2: LMNA, 3: DSP, 4: JUP, 5: DES, 6: TMEM43. The X-axis stands for the isoelectric point (PI), and the Y-axis for the molecular mass (MM).

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  Figure 2. Protein profiles obtained by 2DE pH 3–10. The figures (A–D) are for the gel proteins profiles: (A) Gel E Protein profile patient A12, (B) Gel F Protein profile male control, (C) Gel G Protein profiles of patient A11, the arrow 1 represented PKP2; the arrow 3 represent DSP, (D) Gel H Protein profiles of patient A13; the arrow 1 represent PKP2, the arrow 2 represent LMNA the arrow 3 represent DSP, the arrow 4 represent JUP and the arrow 5 represent DES. The arrow numbers 1, 2, 3, 4, 5, and 6 are for the proteins: 1: PKP2, 2: LMNA, 3: DSP. The X-axis stands for the isoelectric point (PI), and the Y-axis for the molecular mass (MM).