Design
Review
Key result
Arrhythmogenic right ventricular cardiomyopathy is a genetically determined desmosomal disease where molecular testing provides insights for diagnosis, risk stratification, and clinical counseling.
Authors
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Supports molecular testing for ARVC families; leaves open prospective validation of risk stratification utility.
This review highlights the evolution of ARVC/D from a developmental defect to a genetically determined desmosomal cardiomyopathy, emphasizing the clinical utility of molecular genetic testing.
Corrado et al. (2006) conducted a review in Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia. Arrhythmogenic right ventricular cardiomyopathy is a genetically determined desmosomal disease where molecular testing provides insights for diagnosis, risk stratification, and clinical counseling.