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April 15, 2026Frontiers in Immunology0 citationsOpen Access

Mouse TAPBPR shows functional similarity to human TAPBPR in shaping the MHC-I immunopeptidome

JAJuliana Bernardi AggioMWMarcel WackerWGWilliam Guo

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Abstract

. Together, our findings suggest that mouse TAPBPR plays an important role in shaping the MHC-I immunopeptidome by functioning as a peptide editor, similar to its human counterpart.

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Aggio et al. (2026) studied this question.

synapsesocial.com/papers/6a081eafae7f011b61ddeb2bhttps://doi.org/10.3389/fimmu.2026.1756668
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